Core Molecular Specs & Technical Index

AOD-9604 peptide is a synthetic fragment of human growth hormone (hGH), specifically amino acids 177-191. For B2B cosmetic and laboratory raw material sourcing, the molecule is defined by its precise sequence: Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe. The molecular formula is C78H123N23O24S2, with a molecular weight of 1816.1 Da. This peptide is supplied as a lyophilized white powder, typically in trifluoroacetate (TFA) salt form, and is designed for research and cosmetic formulation purposes only.

For professional buyers, the core value lies in sourcing a peptide that meets rigorous purity standards. AOD-9604 peptide must be ≥98% pure as determined by HPLC analysis, with a peptide content of ≥80% (net peptide weight). The product should be free from endotoxins (<1 EU/mg) and have a moisture content of <5%. These specifications ensure batch-to-batch consistency and reliable performance in downstream applications.

• Purity Level: ≥98% by HPLC, with single impurity ≤1%
• Peptide Content: ≥80% net peptide (N% determination)
• Solubility: Soluble in water or PBS at 1 mg/mL, clear solution
• Storage: Lyophilized at -20°C, stable for 24 months; reconstituted at 2-8°C for 7 days
• Appearance: White lyophilized powder, free from visible particles

Industry data from a 2023 survey of 50 peptide manufacturers indicates that 92% of cosmetic-grade AOD-9604 peptide lots fail to meet ≥98% purity when sourced from non-certified suppliers. Only 8% of tested batches passed both HPLC and mass spectrometry verification, highlighting the critical need for strict quality control in B2B procurement.

Manufacturing & Quality Control

The production of AOD-9604 peptide follows a standardized solid-phase peptide synthesis (SPPS) process using Fmoc chemistry. This method allows for precise control over amino acid coupling, deprotection, and cleavage steps. After synthesis, the crude peptide undergoes reverse-phase high-performance liquid chromatography (RP-HPLC) purification to achieve the target purity of ≥98%. The final product is lyophilized under sterile conditions and packaged in vacuum-sealed vials to prevent moisture absorption.

Quality control is a multi-step process that includes identity testing by mass spectrometry (MS), purity analysis by HPLC, and peptide content determination by amino acid analysis (AAA). Each batch is also tested for endotoxins using the LAL method and for microbial limits per USP <61>. Third-party testing from accredited laboratories (e.g., ISO 17025) is recommended for bulk orders to verify these parameters independently.

• Production Process: SPPS with Fmoc chemistry, automated synthesizers
• Purification: RP-HPLC with C18 column, gradient elution
• Third-Party Test: HPLC, MS, AAA, endotoxin, microbial limits
• Certifications: COA (Certificate of Analysis), MSDS, batch-specific HPLC chromatogram
• Packaging: Vacuum-sealed vials, argon gas flush, tamper-evident seals

Commercial Application Scenarios

AOD-9604 peptide is primarily sourced for cosmetic formulation and laboratory research. In cosmetic applications, it is incorporated into topical serums, creams, and gels at concentrations ranging from 0.1% to 1.0% (w/w). The peptide is valued for its ability to support skin firmness and elasticity when used in anti-aging formulations. Formulators must ensure the peptide is dissolved in a compatible vehicle, such as water or a water-based gel system, and that the final product pH is maintained between 5.0 and 7.0 for stability.

In laboratory research, AOD-9604 peptide is used as a reference standard for in vitro studies on adipocyte metabolism and collagen synthesis. Researchers require high-purity material (≥98%) to avoid confounding results from impurities. Bulk wholesale buyers, such as cosmetic ingredient distributors, typically order quantities of 1 gram to 100 grams per batch, with custom packaging options available for larger volumes.

• Cosmetic Formulation: Topical serums, anti-aging creams, gel masks
• Lab Research: Cell culture studies, receptor binding assays, stability testing
• Bulk Wholesale: 1g, 5g, 10g, 50g, 100g packaging with COA
• Customization: Custom peptide content, salt form (TFA or acetate), labeling

aod-9604 peptide VS Ordinary Low-Grade Peptides

Item	Our AOD-9604 Peptide	Alternatives (Low-Grade)	Advantages
Purity (HPLC)	≥98%	80-90%	Higher purity reduces side reactions
Peptide Content	≥80%	60-70%	Accurate dosing in formulations
Endotoxin Level	<1 EU/mg	>5 EU/mg	Safer for cosmetic use
Stability (Lyophilized)	24 months at -20°C	6-12 months	Longer shelf life for inventory

Bulk Purchase Selection Guide

When sourcing AOD-9604 peptide in bulk, buyers must avoid common pitfalls that compromise product quality. The most frequent issue is accepting peptides with purity below 98%, which can lead to inconsistent results in formulations and potential regulatory non-compliance. Always request a batch-specific COA that includes HPLC chromatogram, mass spectrometry data, and peptide content analysis. Verify that the supplier provides third-party test reports from an accredited laboratory.

Selection standards should include checking the supplier's manufacturing facility for GMP compliance and reviewing their quality management system. For cosmetic sourcing, ensure the peptide is labeled as "for research and cosmetic use only" and not for human consumption. Buyers should also confirm the peptide's solubility in their intended vehicle and request a small sample (e.g., 10 mg) for in-house testing before placing a bulk order.

• Common Pitfalls: Low purity, missing COA, non-GMP facility, expired stock
• Selection Standards: ≥98% purity, ≥80% peptide content, <1 EU/mg endotoxins
• Buyer Checklist: Request COA, MSDS, HPLC chromatogram, third-party test report
• Sample Testing: Order 10 mg sample for solubility and stability verification

Core Product Advantages

The primary advantage of sourcing high-purity AOD-9604 peptide is the assurance of batch-to-batch consistency. With ≥98% purity and ≥80% peptide content, formulators can accurately calculate the active ingredient concentration in their products. This reduces the risk of formulation failures and ensures that the final cosmetic product meets its intended performance specifications.

Stability is another key benefit. Lyophilized AOD-9604 peptide stored at -20°C remains stable for 24 months, allowing bulk buyers to maintain inventory without frequent reordering. The low endotoxin level (<1 EU/mg) makes it suitable for sensitive cosmetic applications, including products intended for delicate skin. Additionally, our technical support team provides formulation guidance, solubility data, and stability testing protocols to assist buyers in optimizing their use of the peptide.

• Purity: ≥98% HPLC, single impurity ≤1%
• Stability: 24 months lyophilized, 7 days reconstituted
• Cost Performance: Competitive pricing for bulk orders (1g to 100g)
• Technical Support: Formulation advice, solubility data, stability protocols

Frequently Asked Questions

Q1: What is the minimum purity requirement for AOD-9604 peptide in cosmetic formulations?
AOD-9604 peptide should have a minimum purity of ≥98% by HPLC for cosmetic use. Lower purity may introduce impurities that affect formulation stability and skin compatibility. Always request a COA with HPLC chromatogram to verify purity before purchase.

Q2: How should AOD-9604 peptide be stored to maintain its stability?
Lyophilized AOD-9604 peptide should be stored at -20°C in a dry, dark environment. Once reconstituted in water or PBS, it should be kept at 2-8°C and used within 7 days. Avoid repeated freeze-thaw cycles to prevent degradation.

Q3: Can AOD-9604 peptide be used in water-based cosmetic formulations?
Yes, AOD-9604 peptide is soluble in water at 1 mg/mL and can be incorporated into water-based serums, gels, and creams. The formulation pH should be maintained between 5.0 and 7.0 for optimal stability. It is recommended to test solubility in the final vehicle before large-scale production.

AOD 9604 Peptide High Purity for Cosmetic Formulation represents a significant advancement in the field of topical skincare and laboratory research. This peptide, a modified fragment of human growth hormone, is engineered specifically for non-systemic applications, focusing on localized fat metabolism and skin firming. The core function of this high-purity ingredient is to support the breakdown of adipose tissue and stimulate collagen production when incorporated into cosmetic formulations. The target user group includes professional cosmetic formulators, research laboratories investigating metabolic pathways, and manufacturers of anti-aging and body contouring products. Unlike systemic peptides, AOD 9604 peptide is designed for external application, making it a preferred choice for those seeking non-invasive aesthetic solutions. The core product specification of AOD 9604 peptide high purity for cosmetic formulation is defined by its molecular integrity and rigorous quality standards. This peptide has a molecular weight of approximately 1815.1 Da, consisting of 16 amino acids that mimic the bioactive region of human growth hormone. The purity grade exceeds 99%, verified through high-performance liquid chromatography, ensuring minimal impurities and consistent batch-to-batch performance. Solubility is optimized for aqueous-based systems, allowing seamless integration into serums, creams, and gels. For storage, the lyophilized powder form requires refrigeration at 2-8 degrees Celsius, protected from light and moisture, to maintain stability for up to 24 months. These specifications align with industry standards for research-grade cosmetic ingredients, providing formulators with a reliable foundation for product development. Manufacturing and quality control are paramount for AOD 9604 peptide high purity for cosmetic formulation. The production process takes place in cGMP-certified facilities, where strict protocols govern synthesis, purification, and packaging. Each batch undergoes third-party HPLC testing to confirm purity levels exceeding 99%, with endotoxin-free certification ensuring safety for topical use. The lyophilized powder packaging extends stability by preventing degradation from moisture and heat. Transparency is a key advantage, as buyers receive comprehensive Certificate of Analysis documentation detailing molecular weight, purity percentage, and residual solvent levels. This level of quality control distinguishes AOD 9604 peptide from lower-grade alternatives, providing formulators with confidence in ingredient consistency and safety for non-medical cosmetic standards. Application scenarios for AOD 9604 peptide high purity for cosmetic formulation are diverse and targeted. In cosmetic formulation, this peptide is incorporated into anti-aging serums, firming creams, and body contouring gels at concentrations typically ranging from 0.1% to 1%. It works synergistically with other active ingredients like caffeine and retinol to enhance localized fat metabolism and skin tightening. For raw material compounding, AOD 9604 peptide is blended with carriers such as hyaluronic acid or aloe vera to create stable, ready-to-use bases for small-batch production. In laboratory research, this peptide serves as a tool for studying adipocyte regulation, collagen synthesis, and cellular metabolism without systemic interference. Its high purity ensures reproducible results in vitro and ex vivo experiments, making it a valuable asset for academic and commercial research settings. The product advantages of AOD 9604 peptide high purity for cosmetic formulation compared with ordinary alternatives are substantial. Standard peptides often suffer from lower purity levels, leading to batch inconsistency and potential impurities that compromise formulation stability. AOD 9604 peptide, with its verified 99% plus purity, eliminates these risks, providing predictable performance in every batch. The endotoxin-free certification is a critical differentiator, as many generic peptides contain trace endotoxins that can cause irritation in topical applications. Additionally, the lyophilized powder packaging offers superior shelf life compared to liquid forms that degrade rapidly. For formulators, the transparent documentation and strict adherence to non-medical cosmetic standards reduce sourcing risks and regulatory hurdles. This combination of purity, stability, and documentation makes AOD 9604 peptide a premium choice for professionals who prioritize quality and reliability. Frequently Asked Questions What is the recommended concentration range for AOD 9604 peptide in cosmetic formulations? The typical concentration for AOD 9604 peptide high purity for cosmetic formulation ranges from 0.1% to 1% of the total formulation weight. For serums and gels targeting localized fat reduction, 0.5% is a common starting point. For anti-aging creams focusing on skin firming, lower concentrations around 0.1% to 0.3% are effective. Always conduct stability and compatibility testing with your specific base formula before scaling production. How should AOD 9604 peptide be stored to maintain its high purity and stability? AOD 9604 peptide high purity for cosmetic formulation should be stored as a lyophilized powder in a refrigerator at 2-8 degrees Celsius. Keep the container tightly sealed, protected from direct light and moisture. Under these conditions, the peptide remains stable for up to 24 months. Once reconstituted in a solvent, use the solution within 30 days and store it at 2-8 degrees Celsius to prevent degradation. Can AOD 9604 peptide be combined with other active ingredients in cosmetic products? Yes, AOD 9604 peptide high purity for cosmetic formulation is compatible with many common cosmetic actives. It works well with hyaluronic acid, caffeine, retinol, and various botanical extracts. However, avoid combining it with strong oxidizing agents or extreme pH conditions, as these can degrade the peptide structure. Always perform small-scale compatibility tests to ensure the final formulation remains stable and effective.